MITOGENIC ACTIVITY AND REGENERATION
نویسندگان
چکیده
منابع مشابه
Mitogenic growth factors and nerve dependence of limb regeneration.
Regeneration of the amphibian limb after amputation depends on division of blastemal cells, the progenitor cells of the regenerate. This division is controlled, at least in the early stages of regeneration, by the nerve supply to the blastema. A monoclonal antibody to newt blastema cells has provided evidence that Schwann cells and muscle fibers contribute to the blastema, and identifies blaste...
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Staphylococcus aureus peptidoglycan displayed a marked dose-dependent mitogenic activity for mouse splenocytes and human peripheral blood lymphocytes in vitro, as measured by increased [3H]thymidine incorporation. Similarly it was mitogenic for athymic nude mouse spleen cells, whereas no blastogenic effect was observed in T cell-enriched and B cell-depleted mouse lymphocyte cultures. These data...
متن کاملMitogenic activity of staphylococcal exfoliative toxin.
Exfoliative toxin from Staphylococcus aureus was mitogenic for murine spleen cells. It was primarily active on T lymphocytes but also significantly stimulated B cells from the spleens of nude mice. The mitogenicity was not affected by simple sugar or alpha-methylpyranosides. N-acetylglucosamine and N-acetylgalactosamine inhibited its effect. Exfoliatin was as powerful a mitogen as the enterotox...
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The proliferation of smooth muscle cells in the arterial wall (VSMC) is considered to play a key role in the development of atherosclerosis. To investigate the possible contribution of "stress" (experimentally-induced) to this process, blood from healthy volunteers, ages 21 to 65, screened to exclude major risk factors for coronary heart disease, was assayed for mitogenic activity after the sub...
متن کاملBifidobacteria and Lactobacilli Exhibited Different Mitogenic Activity on Murine Splenocytes
Forty-one strains of Bifidobacterium and Lactobacillus were tested for their ability to induce the proliferation of murine splenocytes using the MTT assay. The tested bifidobacteria induced the apparent proliferation of the murine splenocytes in a strain-dependent manner, while non of the tested lactobacilli showed any mitogenic activity. The bifidobacteria from allergic infants stimulated the ...
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ژورنال
عنوان ژورنال: HERALD of North-Western State Medical University named after I.I. Mechnikov
سال: 2015
ISSN: 2618-9704,2618-7116
DOI: 10.17816/mechnikov20157223-39